This one is an update on some of the creatures that could also be considered suspects in the hunt for sources of MERS-CoV infection of humans.
Of course, camels are the ones we know to be a true risk for infection and there was that 1 bat that was positive for a very small diagnostic PCR product. Cattle contact was also recently listed, with little detail, as a significant risk factor among those acquiring MERS-CoV infection and we also know that cells from camels, horses, alpacas, cattle and goats can be infected and host genome or virus replication of MERS-CoV in the lab, or have the MERS-CoV cellular receptor, DPP4, on their surface.[1,2]
I heard that there will be more bat testing in the future, but we haven't read of any MERS-CoV targeted bat studies since 2013.
So here is the long laundry list of animal testing that needs more work - many of which have been tested in small numbers over limited time periods already - in a graphical form.
Click on image to enlarge. You can also access this from Figshare.[3] |
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